Personal Liquid Biopsy tests are CE-IVD marked

Why get tested?

Personal Cancer Check RNA is a test that allows to determine the presence of genetic fusions, due to translocations, analyising different RNAs in a simultaneous analysis on a single sample.

What the test detects

The purpose of the test is to determine the presence of fused genes in the tumor tissue to support the diagnosis, contribute to the prognosis evaluation an guide the patient in the most appropriate therapeutic choice. The test allows to investigate specifc RNAs transcribed by 10 cancer-specific genes, most commonly involved in the gene fusion phenomenon: ALK, ROS1, RET, NTRK1, NTRK2, NTRK3, FGFR2, FGFR3, PPARG and the region of the exon 14 of MET gene.

How testing works

The analysis can be conducted on different types of tumor tissues: fresh, frozen, formalin-fixed, paraffin-embedded (FFPE) or by fine-needle aspiration (FNA).
The analysis is carried out using a certified kit for in vitro diagnostic (Myriapod NGS Cancer panel DNA, CE-IVD) and entails the retrotranscription, the amplification and sequencing through new generation techniques (NGS). The data obtained are analysed through a complex bioinformatics analysis, to identify the presence of any genetic mutations.
The test uses internal controls for the validation of the procedure and of the analytic session.

Reporting time

Results in 10 -15 working days.

Sensitivity and specificity

Analytical sensitivity, specificityand accuracy > 99%.


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