HLA-G POLYMORPHISMS
Why get tested?
Genetic testing of this variant is indicated: in both individuals of a couple in the case of repeated IVF treatment failures or idiopathic recurrent spontaneous abortions and in the patient in case of heterologous insemination, to identify a donor with the HLA- genotype G compatible.
What the test detects and what the polymorphysm causes
The test identifies the presence of an insertion / deletion of 14 base pairs in the 3 ‘untranslated region of the gene (3 UTR) which has been associated with the increased risk of spontaneous abortions.
How is the test administered on?
The genetic test consists in the execution of a blood sampling, in the extraction of the genomic DNA and in the genotyping of the insertion / deletion of 14 base pairs (rs16375) using the CE-IVD HLA-001 kit, based on the real-time qPCR technique.
Turnaround Times
Results in 20 working days.
Sensitivity and specificity
Analytical sensitivity and specificity > 99,9%.