{"id":1626,"date":"2022-02-07T12:18:40","date_gmt":"2022-02-07T11:18:40","guid":{"rendered":"https:\/\/www.personalgenomics.it\/en\/?post_type=avada_portfolio&#038;p=1626"},"modified":"2022-08-01T12:50:06","modified_gmt":"2022-08-01T10:50:06","slug":"personal-bone-mineralization-defects","status":"publish","type":"avada_portfolio","link":"https:\/\/www.personalgenomics.it\/en\/our-tests\/personal-bone-mineralization-defects\/","title":{"rendered":"PERSONAL BONE MINERALIZATION DEFECTS"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: var(--awb-custom14);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1352px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-1{margin-top:0px!important; margin-right:0px!important;margin-bottom:0px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-1{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-three\" style=\"margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px;\"><h3 class=\"title-heading-center\" style=\"margin:0;color:var(--awb-color7);\">PERSONAL BONE MINERALIZATION DEFECTS<\/h3><\/div><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-2{margin-top:0px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-2{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-2 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-four\" style=\"margin-top:0px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-center\" style=\"margin:0;color:var(--awb-color7);\">Genetic test for defects in bone mineralization<\/h4><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-0{width:100% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-0 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-0{width:100% !important;order : 0;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-0{width:100% !important;order : 0;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-1{ padding-top : 20px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(227,233,236,0.2);background-position: right bottom;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-center\" style=\"max-width:1352px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_2_3 2_3 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 30px 30px 10px 0px;\"><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-center\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-0 fusion_builder_column_inner_1_6 1_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\" md-text-align-left sm-text-align-left\" style=\"text-align:right;\"><style>.fusion-imageframe.imageframe-1{ margin-bottom : 20px;margin-left : 30px;}<\/style><span class=\" fusion-imageframe imageframe-none imageframe-1 hover-type-none\" style=\"max-width:60px;\"><img width=\"128\" height=\"128\" title=\"ico-bone-care\" src=\"https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/ico-bone-care.png\" alt class=\"img-responsive wp-image-1775\"\/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-0{width:16.666666666667% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-0 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 11.52%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 11.52%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-0{width:100% !important;order : 0;}.fusion-builder-nested-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-0{width:100% !important;order : 0;}.fusion-builder-nested-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-1 fusion_builder_column_inner_5_6 5_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-3{margin-top:0px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-3{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-3 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:0px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left\" style=\"margin:0;color:#70bc82;\"><strong>What are the defects in bone mineralization<\/strong><\/h4><\/div><div class=\"fusion-text fusion-text-1\" style=\"text-transform:none;\"><p>Mineralization is a biological process that consists in the deposition of calcium phosphate in the extracellular matrix of bones and all calcified tissues. In addition to the fundamental function of support, the skeletal mineral constitutes the organism&#8217;s main calcium reserve, useful for compensating any imbalances of this vital element.<br \/>\nThere are many pathologies linked to defects in the mineralization process:<\/p>\n<ul>\n<li>When mineralization is reduced or absent, there is a condition of &#8220;soft bone&#8221;, called osteomalacia in adults and rickets in children. In this case, the fragile bone will be susceptible to deformations, fractures and pain.<\/li>\n<li>When mineralization is excessive it is called bone sclerosis, which rather than giving strength and hardness to the bone, induces a reduction in normal remodeling and damage repair, resulting in structural fragility and increased susceptibility to fractures.<\/li>\n<\/ul>\n<p>This type of disorders constitute a heterogeneous group of rare inherited diseases caused by gene mutations on one or more of the many genes involved in the regulation of calcium homeostasis.<\/p>\n<p>Among the main inherited disorders of the mineralization we find:<\/p>\n<ul>\n<li><strong>Hypophosphatasia:<\/strong> it is caused by a defect on the ALPL gene, which encodes the enzyme alkaline phosphatase (TNS-ALP) not tissue-specific, which leads to a reduction in bone mineralization. The clinical spectrum of the disease is extremely variable. The most severe forms present severe rickets, bone fragility, multiple fractures, osteoarticular pain and even neurological affections (convulsions, seizures, encephalopathy, insomnia, anxiety, and depression).<\/li>\n<li><strong><strong>Osteogenesis imperfecta:<\/strong> includes a heterogeneous group of genetic diseases characterized by a decrease in mineralized bone mass, which results in increased skeletal fragility, and a susceptibility to multiple bone fractures of varying severity.<\/li>\n<li><strong>Disorders of phosphate metabolism:<\/strong> it is caused by mutations in the genes that code for proteins that lead to a reduction of phosphate, the ion that with calcium builds up the bone crystal, hydroxyphosphite, in those diseases we find generalized reduced bone mineralization (rickets), bone deformities, fragility fractures, short stature, tooth loss. In addition, there are also mutations on the genes that induce an increase in phosphate in the blood and that are responsible for congenital hyperphosphatemic tumor calcinosis which occurs with the deposition of calcium phosphate crystals in the skin, muscles, tendons and ligaments.<\/li>\n<\/ul>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-1{width:83.333333333333% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-1 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 2.304%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 2.304%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-1{width:100% !important;order : 0;}.fusion-builder-nested-column-1 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-1{width:100% !important;order : 0;}.fusion-builder-nested-column-1 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}<\/style><\/div><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;width:100%;\"><div class=\"fusion-separator-border sep-single\" style=\"border-color:#ffffff;border-top-width:0px;\"><\/div><\/div>\n<div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-center\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-2 fusion_builder_column_inner_1_6 1_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\" md-text-align-left sm-text-align-left\" style=\"text-align:right;\"><style>.fusion-imageframe.imageframe-2{ margin-bottom : 20px;margin-left : 30px;}<\/style><span class=\" fusion-imageframe imageframe-none imageframe-2 hover-type-none\" style=\"max-width:60px;\"><img width=\"128\" height=\"128\" title=\"ico-perche-fare-test-bone-care\" src=\"https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/ico-perche-fare-test-bone-care.png\" alt class=\"img-responsive wp-image-1776\"\/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-2{width:16.666666666667% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-2 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 11.52%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 11.52%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-2{width:100% !important;order : 0;}.fusion-builder-nested-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-2{width:100% !important;order : 0;}.fusion-builder-nested-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-3 fusion_builder_column_inner_5_6 5_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-4{margin-top:0px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-4{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-4 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:0px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left\" style=\"margin:0;color:#70bc82;\"><strong>Why get tested?<\/strong><\/h4><\/div>\n<div class=\"fusion-text fusion-text-2\" style=\"text-transform:none;\"><p>The test represents a useful tool to corroborate the clinical diagnosis and to determine the most suitable therapeutic strategies.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-3{width:83.333333333333% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-3 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 2.304%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 2.304%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-3{width:100% !important;order : 0;}.fusion-builder-nested-column-3 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-3{width:100% !important;order : 0;}.fusion-builder-nested-column-3 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}<\/style><\/div><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;width:100%;\"><div class=\"fusion-separator-border sep-single\" style=\"border-color:#ffffff;border-top-width:0px;\"><\/div><\/div>\n<div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-center\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-4 fusion_builder_column_inner_1_6 1_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\" md-text-align-left sm-text-align-left\" style=\"text-align:right;\"><style>.fusion-imageframe.imageframe-3{ margin-bottom : 20px;margin-left : 30px;}<\/style><span class=\" fusion-imageframe imageframe-none imageframe-3 hover-type-none\" style=\"max-width:60px;\"><img width=\"128\" height=\"128\" title=\"ico-cosa-vede-test-dna-bone-care\" src=\"https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/ico-cosa-vede-test-dna-bone-care.png\" alt class=\"img-responsive wp-image-1777\"\/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-4{width:16.666666666667% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-4 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 11.52%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 11.52%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-4{width:100% !important;order : 0;}.fusion-builder-nested-column-4 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-4{width:100% !important;order : 0;}.fusion-builder-nested-column-4 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-5 fusion_builder_column_inner_5_6 5_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-5{margin-top:0px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-5{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-5 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:0px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left\" style=\"margin:0;color:#70bc82;\"><strong>What the test detects<\/strong><\/h4><\/div>\n<div class=\"fusion-text fusion-text-3\" style=\"text-transform:none;\"><p>The test analyzes the entire coding sequence and related exon \/ intron junctions of the 76 different genes mainly involved.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-5{width:83.333333333333% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-5 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 2.304%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 2.304%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-5{width:100% !important;order : 0;}.fusion-builder-nested-column-5 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-5{width:100% !important;order : 0;}.fusion-builder-nested-column-5 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}<\/style><\/div><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;width:100%;\"><div class=\"fusion-separator-border sep-single\" style=\"border-color:#ffffff;border-top-width:0px;\"><\/div><\/div>\n<div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-center\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-6 fusion_builder_column_inner_1_6 1_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-no-small-visibility fusion-no-medium-visibility\" style=\"text-align:right;\"><span class=\" fusion-imageframe imageframe-none imageframe-4 hover-type-none fusion-no-small-visibility fusion-no-medium-visibility\" style=\"max-width:60px;\"><img width=\"128\" height=\"298\" title=\"ico-come-svolge-test-bone-care\" src=\"https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/ico-come-svolge-test-bone-care.png\" alt class=\"img-responsive wp-image-1778\"\/><\/span><\/div><div class=\" md-text-align-left sm-text-align-left fusion-no-large-visibility\"><style>.fusion-imageframe.imageframe-5{ margin-bottom : 20px;margin-left : 30px;}<\/style><span class=\" fusion-imageframe imageframe-none imageframe-5 hover-type-none fusion-no-large-visibility\" style=\"max-width:140px;\"><img width=\"298\" height=\"128\" title=\"ico-come-svolge-test-orizz-bone-care\" src=\"https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/ico-come-svolge-test-orizz-bone-care.png\" alt class=\"img-responsive wp-image-1779\" srcset=\"https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/ico-come-svolge-test-orizz-bone-care-200x86.png 200w, https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/ico-come-svolge-test-orizz-bone-care.png 298w\" sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 200px\" \/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-6{width:16.666666666667% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-6 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 11.52%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 11.52%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-6{width:100% !important;order : 0;}.fusion-builder-nested-column-6 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-6{width:100% !important;order : 0;}.fusion-builder-nested-column-6 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-7 fusion_builder_column_inner_5_6 5_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-6{margin-top:0px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-6{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-6 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:0px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left\" style=\"margin:0;color:#70bc82;\"><strong>How testing works<\/strong><\/h4><\/div>\n<div class=\"fusion-text fusion-text-4\" style=\"text-transform:none;\"><p>The test consists in a blood test, in the extraction of genomic DNA and in the analysis of the full coding sequence and related exon\/intron junctions of the investigated genes. The analysis is performed using NGS technology.  Only the variants classified as predisposing to the disease will be reported, based on scientific literature data and the classification present in the databases. The test allows for the detection of small sequence variants (single nucleotide changes, insertions \/ deletions of a few base pairs).<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-7{width:83.333333333333% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-7 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 2.304%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 2.304%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-7{width:100% !important;order : 0;}.fusion-builder-nested-column-7 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-7{width:100% !important;order : 0;}.fusion-builder-nested-column-7 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}<\/style><\/div><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;width:100%;\"><div class=\"fusion-separator-border sep-single\" style=\"border-color:#ffffff;border-top-width:0px;\"><\/div><\/div>\n<div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-center\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-8 fusion_builder_column_inner_1_6 1_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\" md-text-align-left sm-text-align-left\" style=\"text-align:right;\"><style>.fusion-imageframe.imageframe-6{ margin-bottom : 20px;margin-left : 30px;}<\/style><span class=\" fusion-imageframe imageframe-none imageframe-6 hover-type-none\" style=\"max-width:60px;\"><img width=\"128\" height=\"128\" title=\"ico-tempi-refertazione-bone-care\" src=\"https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/ico-tempi-refertazione-bone-care.png\" alt class=\"img-responsive wp-image-1780\"\/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-8{width:16.666666666667% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-8 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 11.52%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 11.52%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-8{width:100% !important;order : 0;}.fusion-builder-nested-column-8 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-8{width:100% !important;order : 0;}.fusion-builder-nested-column-8 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-9 fusion_builder_column_inner_5_6 5_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-7{margin-top:0px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-7{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-7 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:0px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left\" style=\"margin:0;color:#70bc82;\"><strong>Reporting time<\/strong><\/h4><\/div>\n<div class=\"fusion-text fusion-text-5\" style=\"text-transform:none;\"><p>Results in 30 working days.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-9{width:83.333333333333% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-9 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 2.304%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 2.304%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-9{width:100% !important;order : 0;}.fusion-builder-nested-column-9 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-9{width:100% !important;order : 0;}.fusion-builder-nested-column-9 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}<\/style><\/div><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;width:100%;\"><div class=\"fusion-separator-border sep-single\" style=\"border-color:#ffffff;border-top-width:0px;\"><\/div><\/div>\n<div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-center\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-10 fusion_builder_column_inner_1_6 1_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\" md-text-align-left sm-text-align-left\" style=\"text-align:right;\"><style>.fusion-imageframe.imageframe-7{ margin-bottom : 20px;margin-left : 30px;}<\/style><span class=\" fusion-imageframe imageframe-none imageframe-7 hover-type-none\" style=\"max-width:60px;\"><img width=\"128\" height=\"128\" title=\"ico-sensibilita-specificita-99-bone-care\" src=\"https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/ico-sensibilita-specificita-99-bone-care.png\" alt class=\"img-responsive wp-image-1781\"\/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-10{width:16.666666666667% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-10 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 11.52%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 11.52%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-10{width:100% !important;order : 0;}.fusion-builder-nested-column-10 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-10{width:100% !important;order : 0;}.fusion-builder-nested-column-10 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-11 fusion_builder_column_inner_5_6 5_6 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-8{margin-top:0px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-8{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-8 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:0px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left\" style=\"margin:0;color:#70bc82;\"><strong>Sensitivity and specificity<\/strong><\/h4><\/div>\n<div class=\"fusion-text fusion-text-6\" style=\"text-transform:none;\"><p>Sensitivity, specificity analytical accuracy > 99%.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-11{width:83.333333333333% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-11 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 2.304%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 2.304%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-11{width:100% !important;order : 0;}.fusion-builder-nested-column-11 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-11{width:100% !important;order : 0;}.fusion-builder-nested-column-11 > .fusion-column-wrapper {margin-right : 1.92%;padding-left : 30px !important;margin-left : 1.92%;}}<\/style><\/div><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-1{width:66.666666666667% !important;margin-top : 0px;margin-bottom : 30px;}.fusion-builder-column-1 > .fusion-column-wrapper {padding-top : 30px !important;padding-right : 30px !important;margin-right : 2.88%;padding-bottom : 10px !important;padding-left : 0px !important;margin-left : 2.88%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-1{width:100% !important;order : 0;}.fusion-builder-column-1 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-1{width:100% !important;order : 0;}.fusion-builder-column-1 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-2{ padding-top : 20px;margin-top : 0px;padding-right : 0px;padding-bottom : 60px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(227,233,236,0.2);background-position: right bottom;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-center\" style=\"max-width:1352px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_4_5 4_5 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-center\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-12 fusion_builder_column_inner_1_4 1_4 fusion-flex-column fusion-flex-align-self-center\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-center fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-12{width:25% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-12 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 7.68%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 7.68%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-12{width:100% !important;order : 0;}.fusion-builder-nested-column-12 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-12{width:100% !important;order : 0;}.fusion-builder-nested-column-12 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-13 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 30px;\"><div ><style>.fusion-imageframe.imageframe-8{ margin-bottom : 20px;}<\/style><span class=\" fusion-imageframe imageframe-none imageframe-8 hover-type-none\"><img width=\"1000\" height=\"684\" title=\"brochure-bone-care\" src=\"https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/brochure-bone-care.png\" alt class=\"img-responsive wp-image-1782\" srcset=\"https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/brochure-bone-care-200x137.png 200w, https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/brochure-bone-care-400x274.png 400w, https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/brochure-bone-care-600x410.png 600w, https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/brochure-bone-care-800x547.png 800w, https:\/\/www.personalgenomics.it\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/brochure-bone-care.png 1000w\" sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 600px\" \/><\/span><\/div><div style=\"text-align:center;\"><style>.fusion-body .fusion-button.button-1{border-radius:8px 8px 8px 8px;}.fusion-body .fusion-button.button-1 .fusion-button-text{text-transform:uppercase;}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-default button-1 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.personalgenomics.it\/pdf\/Personal-Genomics-brochure-patologie-ossee-EN.pdf\"><span class=\"fusion-button-text\">DOWNLOAD THE LEAFLET<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-13{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-13 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 30px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-13{width:100% !important;order : 0;}.fusion-builder-nested-column-13 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-13{width:100% !important;order : 0;}.fusion-builder-nested-column-13 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-14 fusion_builder_column_inner_1_4 1_4 fusion-flex-column fusion-flex-align-self-center\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-center fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-14{width:25% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-nested-column-14 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 7.68%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 7.68%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-14{width:100% !important;order : 0;}.fusion-builder-nested-column-14 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-14{width:100% !important;order : 0;}.fusion-builder-nested-column-14 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-2{width:80% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-2 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 2.4%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 2.4%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-2{width:100% !important;order : 0;}.fusion-builder-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-2{width:100% !important;order : 0;}.fusion-builder-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-3{ padding-top : 20px;margin-top : 0px;padding-right : 0px;padding-bottom : 60px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-4 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1352px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_5 1_5 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-3{width:20% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-3 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 9.6%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 9.6%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-3{width:100% !important;order : 0;}.fusion-builder-column-3 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-3{width:100% !important;order : 0;}.fusion-builder-column-3 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_3_5 3_5 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-9{margin-top:0px!important; margin-right:0px!important;margin-bottom:40px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-9{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-9 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-three\" style=\"margin-top:0px;margin-right:0px;margin-bottom:40px;margin-left:0px;\"><h3 class=\"title-heading-center\" style=\"margin:0;\">Fill out the form for further information<\/h3><\/div><div role=\"form\" class=\"wpcf7\" id=\"wpcf7-f125-o1\" lang=\"it-IT\" dir=\"ltr\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/en\/wp-json\/wp\/v2\/avada_portfolio\/1626#wpcf7-f125-o1\" method=\"post\" class=\"wpcf7-form init\" novalidate=\"novalidate\" data-status=\"init\">\n<div style=\"display: none;\">\n<input type=\"hidden\" name=\"_wpcf7\" value=\"125\" \/>\n<input type=\"hidden\" name=\"_wpcf7_version\" value=\"5.6.1\" \/>\n<input type=\"hidden\" name=\"_wpcf7_locale\" value=\"it_IT\" \/>\n<input type=\"hidden\" name=\"_wpcf7_unit_tag\" value=\"wpcf7-f125-o1\" \/>\n<input type=\"hidden\" name=\"_wpcf7_container_post\" value=\"0\" \/>\n<input type=\"hidden\" name=\"_wpcf7_posted_data_hash\" value=\"\" \/>\n<input type=\"hidden\" name=\"_wpcf7cf_hidden_group_fields\" value=\"[]\" \/>\n<input type=\"hidden\" name=\"_wpcf7cf_hidden_groups\" value=\"[]\" \/>\n<input type=\"hidden\" name=\"_wpcf7cf_visible_groups\" value=\"[]\" \/>\n<input type=\"hidden\" name=\"_wpcf7cf_repeaters\" value=\"[]\" \/>\n<input type=\"hidden\" name=\"_wpcf7cf_steps\" value=\"{}\" \/>\n<input type=\"hidden\" name=\"_wpcf7cf_options\" value=\"{&quot;form_id&quot;:125,&quot;conditions&quot;:[],&quot;settings&quot;:{&quot;animation&quot;:&quot;yes&quot;,&quot;animation_intime&quot;:200,&quot;animation_outtime&quot;:200,&quot;conditions_ui&quot;:&quot;normal&quot;,&quot;notice_dismissed&quot;:false}}\" \/>\n<input type=\"hidden\" name=\"_wpcf7_recaptcha_response\" value=\"\" \/>\n<\/div>\n<style>\n                .uacf7-uacf7style-125 label {\n                    color: ;\n                    background-color: ;\n                    font-size: px;\n                    font-family: ;\n                    font-style: normal;\n                    font-weight: normal;\n                    padding-top: px;\n                    padding-right: px;\n                    padding-bottom: px;\n                    padding-left: px;\n                    margin-top: px;\n                    margin-right: px;\n                    margin-bottom: px;\n                    margin-left: px;\n                }\n                .uacf7-uacf7style-125 input[type=\"email\"],\n                .uacf7-uacf7style-125 input[type=\"number\"],\n                .uacf7-uacf7style-125 input[type=\"password\"],\n                .uacf7-uacf7style-125 input[type=\"search\"],\n                .uacf7-uacf7style-125 input[type=\"tel\"],\n                .uacf7-uacf7style-125 input[type=\"text\"],\n                .uacf7-uacf7style-125 input[type=\"url\"],\n                .uacf7-uacf7style-125 input[type=\"date\"],\n                .uacf7-uacf7style-125 select,\n               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class=\"wpcf7-list-item-label\">Healthcare professinal<\/span><\/label><\/span><\/span><\/span><\/div>\n<div class=\"col-sm-6\" style=\"margin-top: 15px;\"><label> <span class=\"wpcf7-form-control-wrap\" data-name=\"your-name\"><input type=\"text\" name=\"your-name\" value=\"\" size=\"40\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"First name *\" \/><\/span> <\/label><\/div>\n<div class=\"col-sm-6\" style=\"margin-top: 15px;\"><label> <span class=\"wpcf7-form-control-wrap\" data-name=\"cognome\"><input type=\"text\" name=\"cognome\" value=\"\" size=\"40\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"Last name *\" \/><\/span> <\/label><\/div>\n<div class=\"col-sm-12\" style=\"margin-top: 15px;\"><label> <span class=\"wpcf7-form-control-wrap\" data-name=\"your-email\"><input type=\"email\" name=\"your-email\" value=\"\" size=\"40\" class=\"wpcf7-form-control wpcf7-text wpcf7-email wpcf7-validates-as-required wpcf7-validates-as-email\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"Email *\" \/><\/span> <\/label><\/div>\n<div class=\"col-sm-6\" style=\"margin-top: 15px;\"><label> <span class=\"wpcf7-form-control-wrap\" data-name=\"telefono\"><input type=\"tel\" name=\"telefono\" value=\"\" size=\"40\" class=\"wpcf7-form-control wpcf7-text wpcf7-tel wpcf7-validates-as-required wpcf7-validates-as-tel\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"Phone *\" \/><\/span> <\/label><\/div>\n<div class=\"col-sm-6\" style=\"margin-top: 15px;\"><label> <span class=\"wpcf7-form-control-wrap\" data-name=\"regione\"><input type=\"text\" name=\"regione\" value=\"\" size=\"40\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"Country *\" \/><\/span> <\/label><\/div>\n<div class=\"col-sm-12\" style=\"margin-top: 15px;\"><label> <span class=\"wpcf7-form-control-wrap\" data-name=\"your-message\"><textarea name=\"your-message\" cols=\"40\" rows=\"10\" class=\"wpcf7-form-control wpcf7-textarea\" aria-invalid=\"false\" placeholder=\"Message\"><\/textarea><\/span> <\/label><\/div>\n<div class=\"col-sm-12\" style=\"font-size:13px; line-height:30px; margin-top: 10px; margin-bottom: 10px;\"><span class=\"wpcf7-form-control-wrap\" data-name=\"newsletter\"><span class=\"wpcf7-form-control wpcf7-acceptance optional\"><span class=\"wpcf7-list-item\"><label><input type=\"checkbox\" name=\"newsletter\" value=\"1\" aria-invalid=\"false\" \/><span class=\"wpcf7-list-item-label\">I consent to the processing of my Personal Data for the purposes detailed under paragraph 2.3 to send information and\/or advertisement material, from the Company or other SOL Group companies, and particularly via e-mail, fax, MMS or SMS messages.<\/span><\/label><\/span><\/span><\/span><\/div>\n<div class=\"col-sm-12\" style=\"font-size:13px; margin-bottom:20px;\"><span class=\"wpcf7-form-control-wrap\" data-name=\"privacy\"><span class=\"wpcf7-form-control wpcf7-acceptance\"><span class=\"wpcf7-list-item\"><label><input type=\"checkbox\" name=\"privacy\" value=\"1\" aria-invalid=\"false\" \/><span class=\"wpcf7-list-item-label\">* I, the undersigned, having read the <a href=\"\/privacy-policy\/\" target=\u201d_blank\u201d title=\"Privacy Policy\"><strong>privacy notice reported here<\/strong><\/a>, which I declare to have read in all its parts, concerning the processing of my personal data required to navigate the Website.<\/span><\/label><\/span><\/span><\/span><\/div>\n<div class=\"col-sm-12\" style=\"margin-top:10px;\"><input type=\"submit\" value=\"Send request\" class=\"wpcf7-form-control has-spinner wpcf7-submit\" \/><\/div>\n<style>\n.wpcf7-form input {\n    margin-bottom: 10px;\n}\n<\/style>\n<\/div>\n<\/div>\n<div class=\"fusion-alert alert custom alert-custom fusion-alert-center wpcf7-response-output fusion-alert-capitalize alert-dismissable\" role=\"alert\" style=\"border-width:1px;\"><div class=\"fusion-alert-content-wrapper\"><span class=\"fusion-alert-content\"><\/span><\/div><button type=\"button\" class=\"close toggle-alert\" data-dismiss=\"alert\" aria-label=\"Close\">&times;<\/button><\/div><\/form><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-4{width:60% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-4 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.2%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.2%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-4{width:100% !important;order : 0;}.fusion-builder-column-4 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-4{width:100% !important;order 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0px;}<\/style><\/div>\n<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":1774,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":[],"portfolio_category":[42],"portfolio_skills":[],"portfolio_tags":[],"_links":{"self":[{"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/avada_portfolio\/1626"}],"collection":[{"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/avada_portfolio"}],"about":[{"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/types\/avada_portfolio"}],"author":[{"embeddable":true,"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/comments?post=1626"}],"version-history":[{"count":10,"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/avada_portfolio\/1626\/revisions"}],"predecessor-version":[{"id":1705,"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/avada_portfolio\/1626\/revisions\/1705"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/media\/1774"}],"wp:attachment":[{"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/media?parent=1626"}],"wp:term":[{"taxonomy":"portfolio_category","embeddable":true,"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/portfolio_category?post=1626"},{"taxonomy":"portfolio_skills","embeddable":true,"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/portfolio_skills?post=1626"},{"taxonomy":"portfolio_tags","embeddable":true,"href":"https:\/\/www.personalgenomics.it\/en\/wp-json\/wp\/v2\/portfolio_tags?post=1626"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}